rainbow of DNA oligo excimers

March 5, 2009 at 3:16 pm | | literature

My friend Yin Nah over in the Kool lab just published a cool paper in JACS. By attaching fluorophores to deoxyriboside monomers (what they call “fluorosides”), they can then assemble different oligos. Because different sequences have different fluorophores close to each other in different orders, they can make exciplexes that fluoresce at a variety of colors … all pumped at the same (albeit UV) wavelength.


The Kool lab has been working with pyrene and others in the past, but this recent paper expands the fluorophores and colors the oligos produce. And they’ve been doing some cell and zebrafish embryo labeling, too.

Very beautiful.


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  1. the rainbow picture is the mecca of all chemists studying photoluminescence. and that is one fabulous rainbow picture!

    also: exciplexes would be *such* a rad name for a band. if you form it i want to play the cowbell!

    Comment by joel — March 5, 2009 #

  2. they almost look like crayons! WANT!!!

    Comment by psi*psi — March 5, 2009 #

  3. That’s why it’s called the Kool lab!

    Comment by orange — March 10, 2009 #

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