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1. I think the Japanese scientist Hideo Hosono, who discoverd the iron-based superconductors, could win the physics prize this year.

   Comment by Kagayaki — September 21, 2018 #

2. I agree that the molecular motor people have a great chance for the chemistry price. However, I would put my money on CRISPR. I hope that a microbiologist is included along with Doudna and Charpentier. I also think that David Allis has a really good chance for winning based on the chemistry of chromatin modification.

   For the physiology/medicine prize I think nuclear receptor signaling (Chambon, Evans, O’Malley) is a possibility as well as cell adhesion (Hynes, Ruoslahti, Takeichi). Hypoxia is a also a good one (Kaelin and Semenza). And let’s not forget about leptin (Freidman, Leibel) and fat metabolism.

   Lastly, I would like to place a plug for my podcast, The Inner Scientist, which is available on iTunes and Stitcher. I talk in depth with prominent scientists about their big discoveries in biomedical research. Please listen, review and spread the word.

   Comment by Joe M — September 22, 2018 #

3. Physiology or Medicine ; Pierre Chambon & Ronald Evans

   Chemistry ; Steven V. Ley

   Physics ; Anton Zeillinger, Alain Aspect & Nicolas Gisin

   Comment by Martin — September 24, 2018 #

4. […] Marrack) Physics: Dark matter (Sandra Faber, Margaret Geller, Jerry Ostriker, Helen Quinn) https://blog.everydayscientist.com/?p=3662 For predictions from past years, here are some links I compiled in a previous thread: […]

   Pingback by Nobel Prize 2018 Announcements | Page 2 | Physics Forums — September 24, 2018 #

5. […] Another set of predictions for 2018, from a biophysicist blogger: https://blog.everydayscientist.com/?p=3662 For predictions from past years, here are some links I compiled in a previous thread: […]

   Pingback by Nobel Prize 2018 Announcements | Page 3 | Physics Forums — September 24, 2018 #

6. For the Peace Prize -2018, my predictions are in following orders 1) Ragip Zarkaloue( born 1948) of Marmara, Istanbul, Turkey , – a human Rights activist [ https://en.wikipedia.org/wiki/Rag%C4%B1p_Zarakolu%5D 2) Nadia Mirad – An international advocate against sexual violence [ https://en.wikipedia.org/wiki/Nadia_Murad%5D 3) Prof. Sankha Suvra Mitra and Runa Mitra of Eastern India Palliative care ( EIPC) for they are pioneer in Palliative care movement in West Bengal, India ,for cancer patients[ https://palliativecareindia.wordpress.com/…/eastern… /] .

   For the Physics Prize -2018, my predictions are in following orders)Prof. Allan Guth ( born 1947) for his cosmic Inflation theory in Big Bang 2) Mr. Rupak Bhattacharya ( Born 1974) s/o Late Bholanath Bhattacharya & Late Bani Bhattacharya of Residence 7/51 Purbapalli, PO -Sodepur ,Dist 24 Parganas ( north) kolkata -110, West Bengal, India for his first published concepts of a) “Tachyon Particles”–a F.T.L Particles[ http://www.openscienceonline.com/journal/archive2…] &[ http://chadorzel.com/…/24/faster-than-a-speeding-photon/ ] ,b) For his concepts of “Multiple Bubble Universes or parallel Universe[ https://totallydrug-resistanttbemergesinindia.blogspot.co…] ” c) Zero Rest mass particles at Planck’s epoch [ https://www.slideshare.net/…/research-reviews-journal… & [ https://journalofscience.org/…/article/download/1964/1825/ ] &[ https://globaljournals.org/…/E-Journal_GJSFR_(A)_Vol_17…] -he published 3) My third choice is Geoffrey W.Marcy & Michael Mayor for they first proposed existences of extra solar exoplanets

   For the Medicine & Physiology prize predictions are in following orders 1) Denis. J salmon, Nicholas Lyndon,Bram. J.Duker for the drug imatinib used in CML 2) Emmanuel Charpenter and Jennifer A Dunda( born 1964) for their Fundamental work for CRISPER/ cas9 for Gene editing 3) Jacques FA Millar ( born 1931) for T cells and B cells has different role in immune response and GVHD and in treatment of cancer 4) J. Salmon for his discovery of Her2Neu oncogenes in breast and it’s role in therapy of breast carcinoma with infusion of Herceptin

   For chemistry prize my prediction is for Paul Alvisatos & Chad A Markan for DNA nano technology

   Comment by professor Pranab Kumar Bhattacharya — September 27, 2018 #

7. For the Physics Prize -2018, my predictions are in following orders)Prof. Allan Guth ( born 1947) for his cosmic Inflation theory in Big Bang 2) Mr. Rupak Bhattacharya ( Born 1974) s/o Late Bholanath Bhattacharya & Late Bani Bhattacharya of Residence 7/51 Purbapalli, PO -Sodepur ,Dist 24 Parganas ( north) kolkata -110, West Bengal, India for his first published concepts of a) “Tachyon Particles”–a F.T.L Particles[ http://www.openscienceonline.com/journal/archive2…] &[ http://chadorzel.com/…/24/faster-than-a-speeding-photon/ ] ,b) For his concepts of “Multiple Bubble Universes or parallel Universe[ https://totallydrug-resistanttbemergesinindia.blogspot.co…] ” c) Zero Rest mass particles at Planck’s epoch [ https://www.slideshare.net/…/research-reviews-journal… & [ https://journalofscience.org/…/article/download/1964/1825/ ] &[ https://globaljournals.org/…/E-Journal_GJSFR_(A)_Vol_17…] -he published 3) My third choice is Geoffrey W.Marcy & Michael Mayor for they first proposed existences of extra solar exoplanets

   Comment by professor Pranab Kumar Bhattacharya — September 27, 2018 #

8. For the Medicine & Physiology prize predictions are in following orders 1) Denis. J salmon, Nicholas Lyndon,Bram. J.Duker for the drug imatinib used in CML 2) Emmanuel Charpenter and Jennifer A Dunda( born 1964) for their Fundamental work for CRISPER/ cas9 for Gene editing 3) Jacques FA Millar ( born 1931) for T cells and B cells has different role in immune response and GVHD and in treatment of cancer 4) J. Salmon for his discovery of Her2Neu oncogenes in breast and it’s role in therapy of breast carcinoma with infusion of Herceptin

   For chemistry prize my prediction is for Paul Alvisatos & Chad A Markan for DNA nano technology

   Comment by professor Pranab Kumar Bhattacharya — September 27, 2018 #

9. For the Peace Prize -2018, my predictions are in following orders 1) Ragip Zarkaloue( born 1948) of Marmara, Istanbul, Turkey , – a human Rights activist [ https://en.wikipedia.org/wiki/Rag%C4%B1p_Zarakolu%5D 2) Nadia Mirad – An international advocate against sexual violence [ https://en.wikipedia.org/wiki/Nadia_Murad%5D 3) Prof. Sankha Suvra Mitra and Runa Mitra of Eastern India Palliative care ( EIPC) for they are pioneer in Palliative care movement in West Bengal, India ,for cancer patients[ https://palliativecareindia.wordpress.com/…/eastern… /] .

   Comment by professor Pranab Kumar Bhattacharya — September 27, 2018 #

10. https://health.economictimes.indiatimes.com/news/industry/us-japanese-pair-win-nobel-prize-for-cancer-research/66036276#comment-4124687457 My predictions for 2018 Nobel prize in Medicine and physiology ( in the face book of Nobel prize post of 24&25 September 2018 and in the comments of “2018 Nobel prize predictions’ in every day science on September 20,2018 blog comment of 24 th September 2018) were based on for the treatment of cancer and my order of choice were 1) Imatinib 2) CRISPER/ cas9 3) T cells role in immune response in GVHD and in treatment of cancer 4) Herceptin and Her2Nue oncogenes. The karoliniska institutete Nobel Assembly choiced 2018 Nobel prize for a T cells protein ( CTL A4) which is cytotoxic T lymphocytes protein molecules on T cells receptors which trigger a full blown immune response against cancer cells particularly for malignant melanoma cells,lung cancer cells. CTLA4 is infact a immune response check point protein that acts as a brake on immune cells called T cells and there by unleashing our immune To cells to attack tumors cells ( by T-T) specified antigens. These T cells receptors bind to the structure recognized as nonself and that T-T interaction immune system are engaged in defense for cancer cells
    The CTLA4 is a T cell receptors protein and functions as a brake on T cells and are required a full blown immune response by T cells and this can attack against anything may be a virus, a microorganisms,a cancer cells and destruction of even normal tissues by TNF.Thus a balance is always required between acceletor and a brake
    An antibody that could bind to CTLA4 and block it’s functions was required and developed later since 1990. CTLA4 block ed and disengage the T cell brake and unleashing the immune system to attack cancer cells. Allison and his co-workers performed a first experiment at end of 1994 in mice devoloped melanoma, where,this cancer was cured due to more and more anti tumor cytotoxic T cells activity.Most promising results came out in 2010 in clinical study for advanced melanoma and in several patients sign of metastatic deposit disappeared.
    Honjo etall discovered a different T cells receptors protein called PD-1, which also acts as a brake on the immune system
    So PD1 also became a target for different cancer including lung cancer,a major killer for men across the world and PD1Block therapy is known as immune check point therapy.
    In recent years clnical works on drugs that inhibit CTLA4 & PD-1 have shown to be effective in lung cancer ( though questionable in disease free and quality life survival rate ) , Renal cancer ( R.C.c) , lymphoma, melanoma, though it has serious side effects like over activity of immune response,severe others auto immune reactions leading to others auto immune disease, SLE, severe bone marrow suppression.such a drug that inhibit CTLA4 is known as ” Ipilimumab” won approval from FDA in 2014 for use in malignant melanoma patients
    But the drug is very costly in all over the world that very few individual can afford treatment with this drug, due to exclusive marketing Right and Intellectual property Right.No doubt this drug acts wonder for melanoma patients
    When combined CTLA4 with PD-1 and PDL2 blocked antibody ( much costly than Ipilimumab) it acts on wide variety of solid cancer.other drugs available in USA market are Nivolumab,and pembrolizumab.
    The check point therapy of T cell immune system has been attempted by various scientist for more than hundred years and check point immuno therapy can revolunize cancer therapy when it’s price will be in reach to common people of 3 Rd world countries and can show in near future how cancer can be managed
    The Nobel Assembly at karoliniska institutete so decided to award the 2018 Nobel prize in Medicine and physiology to James P Allison PhD ( born 1948) of university of the Texas ( MD Anderson cancer center) and Tasuku Honjo ( born 1942) of kyto university Japan who pioneered this work in 1992 by Prof Honjo T ( EMBO j 1992;11(11);3887-3895 and in j.Exp.Med2000;192(7);1027-34 as original research article and James P Allison ( published in Science as comment 1996; 271(5256);1734-36

    Author -: Professor Dr. Pranab Kumar Bhattacharya, Professor of Pathology ;Murshidabad Medical college, Berhampore court ;Murshidabad ; West Bengal ; India
    Copy right of the article-: strictly belongs to Professor Df. Pranab Kumar Bhattacharya as per copy right laws and acts of intellectual property Right( IPR)

    Comment by professor Pranab Kumar Bhattacharya — October 4, 2018 #

11. My Predictions In the comment of Post At face book of http://www.nobelprize.org “Who will be awarded a Nobel Prize this year? The announcement of the 2018 Nobel Prizes will be broadcast live on our Facebook page and on http://www.nobelprize.org.” of 24th September 2018 in NO 2 choices ] It was Nadia Mirad – an international Advocate against Sexual violence As the Post was on 24th September Post and also in the comment of the blog Everyday scientist ” 2018 Nobel prize predictions ”
    ProfPranab Kr Bhattacharya For the Peace Prize -2018, my predictions are in following orders 1) Ragip Zarkaloue( born 1948) of Marmara, Istanbul, Turkey , – a human Rights activist [ https://en.wikipedia.org/wiki/Rag%C4%B1p_Zarakolu%5D 2) Nadia Mirad – An international advocate against sexual violence [ https://en.wikipedia.org/wiki/Nadia_Murad%5D 3) Prof. Sankha Suvra Mitra and Runa Mitra of Eastern India Palliative care ( EIPC) for they are pioneer in Palliative care movement in West Bengal, India ,for cancer patients[ https://palliativecareindia.wordpress.com/…/eastern… /] . 4) world Food Program working in Syria and Yemen on which 8 million people Iam really feeling proud that this year two of my early Predictions came true that i) Medicine Prize will go for Cancer therapy and one of my Choices was T cell in treatment of the cancer though the persons awarded did not matched with my predictions but the theme of Cancer therapy and Cytotoxic T Lymphocyte in cancer therapy was choiced by Nobel assembly of Karoliniska institutet and 2] in Peace Prize Nadia Mirad the person I exactly predicted also Won the Peace Nobel prize. Thanks to Nobel peace Prize committee of Oslo for awarding Nadia Mirad also

    Comment by professor Pranab Kumar Bhattacharya — October 5, 2018 #

12. My Predictions In the comment of Post Who will be awarded a Nobel Prize this year? The announcement of the 2018 Nobel Prizes will be broadcast live on our Facebook page and on http://www.nobelprize.org. of 24th September 2018 in NO 2 choices ] It was Nadia Mirad – an international Advocate against Sexual violence As the Post was on 24th September Post
    ProfPranab Kr Bhattacharya For the Peace Prize -2018, my predictions are in following orders 1) Ragip Zarkaloue( born 1948) of Marmara, Istanbul, Turkey , – a human Rights activist [ https://en.wikipedia.org/wiki/Rag%C4%B1p_Zarakolu%5D 2) Nadia Mirad – An international advocate against sexual violence [ https://en.wikipedia.org/wiki/Nadia_Murad%5D 3) Prof. Sankha Suvra Mitra and Runa Mitra of Eastern India Palliative care ( EIPC) for they are pioneer in Palliative care movement in West Bengal, India ,for cancer patients[ https://palliativecareindia.wordpress.com/…/eastern… /] . 4) world Food Program working in Syria and Yemen on which 8 million people Im Really proud that this year Two of my Predictions came true i) Medicine Prize will go for Cancer therapy and one of my Choices was T cell in treatment of the cancer though the persons awarded did not matched with my predictions but the theme of Cancer therapy and Cytotoxic T Lymphocyte in cancer therapy was choiced by NObel assembly of Karoliniska institutet and in Peace Prize Nadia Mirad the person I predicted also Won the Peace Nobel prize Thanks to Nobel peace committee OF Oslo

    Comment by professor Pranab Kumar Bhattacharya — October 5, 2018 #

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