These are single fluorescent molecules imaged using a microscope and a hand-held consumer digital SLR camera (i.e. Nikon D90):
I think that’s pretty impressive. Usually, we use expensive, cooled CCD cameras which are very sensitive and designed for scientific imaging. Here, I used a (cheaper) conventional digital camera and even got a color image. This is possible in part because this fluorophore (one of the Moerner/Twieg labs’ DCDHF dyes) is super bright and long-lived!